Aeris Therapeutics, Inc.

Clinical Trials

Aeris is conducting clinical studies evaluating the Aeris Biologic Lung Volume System in phase II studies. The goal of the studies is to assess the safety and efficacy of the BLVR system using different treatment doses in patients with advanced homogeneous or upper lobe emphysema that is not responsive to medical therapy. All patients that meet the study inclusion / exclusion criteria and choose to participate receive the BLVR treatment.

Further information regarding clinical studies sponsored by Aeris may be found at www.clinicaltrials.gov; enter “Aeris” in the “Search Clinical Trials” box.

Participation Criteria for Aeris BLVR Clinical Trial

Criteria for participation in this trial include:

· ≥ 40 years of age

· Advanced homogeneous or upper lobe predominant emphysema that is disabling despite medical therapy

· Able to tolerate bronchoscopy

· Have not smoked for 4 months prior to and during study participation

· Have not had previous surgical procedures of the lung

· Have not had clinically significant asthma, chronic bronchitis, or bronchiectasis

Patients who believe they meet these participation criteria and are interested in learning more about the BLVR clinical trial, should review the Participating Sites for a BLVR clinical trial site near their home, and should contact the Site’s Study Coordinator.

Participating Sites – Aeris BLVR Clinical Trial

Active Sites:

UNITED STATES

Alabama

University of Alabama, Birmingham

Dr. Mark Dransfield – Principal Investigator

Study Coordinator: Sherry Tidwell (205-996-6602)

Stidwell@uab.edu

Arizona
Pulmonary Associates, Phoenix

Dr. Mark Gotfried – Principal Investigator

Study Coordinator: Dr. Li Yi Fu (602-258-4951)

palyf@aol.com